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The Champions League action returns mid-week ahead of a ram-packed Christmas calendar in the coming weeks.
Odds Now's Brad Walker kicks-off our coverage with a 5/1 accumulator across the first round of matches on Tuesday.
The pressure is on Mikel Arteta's men, who succumbed to a 1-0 loss at Inter Milan last time out in this competition.
Arsenal currently find themselves in 12th, two points adrift of the automatic qualification spots heading into matchday five.
To their credit, the Gunners returned to winning ways against Nottingham Forest at the weekend after failing to come out on top in any of their previous three in all competitions.
And they prepare to face a Sporting Lisbon side who are still coming to terms with the loss of former manager Ruben Amorim, who has since departed for Manchester United.
Joao Pereira has replaced him in the Sporting dugout but, despite a winning start against third-division side Amarante at the weekend, eyes will be on 'The Lions' to see if they are able to replicate the form prior to Amorim's departure.
All in all, Arsenal look to have turned a corner after the return of several key players from injury and should have too much quality for their Portuguese counterparts here.
Atletico Madrid have bounced back from a 1-0 defeat to Real Betis last month in impressive fashion.
Diego Simeone's side have recorded five consecutive victories on the bounce in all competitions, including a 2-1 home win over Alaves on Saturday.
The Spanish club have been hit-and-miss in Europe so far, winning two and losing two of their first four matches, but will surely fancy their chances of recording a third victory in this one.
Opponents Sparta Prague are winless in their last three in the Champions League and, in reality, are several levels below Simeone's men in terms of quality.
A lack of clean sheets in recent outings is alarming - Sparta have picked up one in their last 11 in all competitions - and are about to face an 'Atleti' side who have scored at least two goals in four of their last five.
The final selection centres on a meeting of two of the continent's 'big-hitters'.
Vincent Kompany's Bayern Munich have hardly put a foot wrong domestically and are yet to taste defeat in the German Bundesliga.
Their form hasn't been as convincing in Europe though, having lost two of their four matches in the Champions League, against Aston Villa and Barcelona.
However, both of those defeats came on the road, with Bayern not only winning their two outings at the Allianz Arena but also scoring 10 goals in the process.
Compare with the form of PSG, who have won just one of their four mathces in the competition.
Their sole away outing in the Champions League came in a 2-0 loss at Arsenal, a game which saw the Parisiens record a measly 0.4xG across the 90 minutes.
PSG have also kept just two clean sheets across their Ligue 1 and Champions League outings.
It shouldn't come as a surprise to see them enter wide underdogs at on odds-against 9/2.