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Premier League leaders Liverpool make the difficult trip to Aston Villa knowing victory will see them move 10 points clear of second-placed Arsenal.
But where does the value lie ahead of kick-off at Villa Park?
Our tipster Brad Walker (@brad_TWalker) runs you through all of the key details.
Hosts Aston Villa have returned to the kind of home form which saw them secure a spot in the Champions League last season.
Unai Emery's men endured an eight-match winless run at Villa Park between the end of October and the beginning of December, significantly hindering their league position in the process.
Nevertheless, the Villains head into Wednesday evening unbeaten in their last 12 games on home soil.
The latest saw them play out a disappointing 1-1 draw with relegation-threatened Ipswich, though Emery will have been encouraged by substitute cameos from the likes of Marcus Rashford and Marcos Asensio.
Both were added to the Villa ranks during the January window and saw plenty of involvement in their maiden appearances wearing claret and blue.
Meanwhile, visitors Liverpool head to the west Midlands without a defeat in their last 21 league outings but were less than convincing in their 2-1 victory over Wolves at Anfield on Sunday.
Arne Slot's side initially raced into a 2-0 lead in the first half, courtesy of goals from Luis Diaz and Mohamed Salah, before Matheus Cunha's strike made for a nervy watch for those associated with the Merseysiders in the second half.
Ultimately, Liverpool got over the line to regain a seven-point lead at the league summit, but the performance acted as a timely reminder that nothing has been won yet.
The away side will be boosted by the availability of midfielder Curtis Jones, who was forced to sit out the Wolves clash through suspension.
To say the home crowd were on edge at Anfield on Sunday would be an understatement.
Liverpool failed to record a single shot in the second half compared to the 10 Wolves recorded on Alisson Becker's goal.
In fact, only a last-ditch Jarell Quansah tackle prevented the visitors from nicking a point against the leaders, who have now managed only two clean sheets in their last seven league matches.
The pressure is on Liverpool ahead of their trip to Villa Park, which will be their third of five league games across a 15 day span. Such a run will inevitably lead to some squeaky moments for any side, suggesting Villa could possibly get some joy in the final third on Wednesday.
I'm not willing to take on Liverpool on the winner's line given the imperious form they've enjoyed over the previous months, but I do think the game could provide the aforementioned Marcus Rashford an opportunity to continue his momentum from the weekend.
The English forward entered the fray at the break against Ipswich and had an immediate impact for his new club, recording three shots on the Tractor Boys' goal.
One such effort thundered off the Ipswich crossbar for Ollie Watkins to convert and level the score, while another of Rashford's efforts also drew a save from Alex Palmer in the away goal.
The performance will likely earn the Mancunian a start in this one and see him lineup against a Liverpool defence which has conceded 30 shots on goal in their last three league outings.
Slot's backline isn't performing anywhere near the levels seen during the early stages of the campaign and can certainly be exploited, particularly in the midst of a hectic run like the one Liverpool are currently enduring.
Yet, Rashford still comes in at even money to record over 1.5+ shots across the 90 minutes - a feat he managed in the 45 he played at the weekend.
That price is more than worth a stab for me and it may even be worth backing him to record over 2.5 at a hefty 14/5, given the defensive fragilities of the away side.
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